Some studies have reported trends toward improvement in fasting blood glucose, glycated albumin, 2-hour values in oral glucose tolerance testing, and HbA1c when 5-ALA is taken together with SFC, an iron component. The uploaded materials also introduce studies related to Type 2 diabetes and mitochondrial diabetes, suggesting that 5-ALA may help support glucose metabolism.

However, the effect on blood glucose varies from person to person. Results may differ depending on the state of diabetes, pancreatic function, insulin resistance, diet, exercise, and current medications. Therefore, 5-ALA should not be used as a substitute for diabetes medication or insulin based on personal judgment. It should be understood as a compound that may support glucose metabolism.

Special caution is needed for people who are already using diabetes medication. Because blood glucose levels may change, anyone considering taking 5-ALA should do so carefully under medical supervision, with appropriate blood glucose monitoring.