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Explore our research and technology
in greater depth.

Our public materials explain the scientific background, technology concepts, and research history behind Biozipcode, Inc.’s R&D in more detail than a website page can.

Our work centers on research into “diabetes stem cells” (DSCs), a proposed research term and Biozipcode™ cell-targeting technology, with applications under study in diabetes, biomarkers, DDS, cancer, tissue regeneration, and other areas.

Alongside company and technology overview PDFs, this page provides access to selected publications, patents and intellectual property, and videos and presentations so you can examine the research in greater detail.

These materials offer an introduction for pharmaceutical companies, universities and research institutions, medical institutions, diagnostics and medical device companies, and others considering co-development or technology licensing.

FEATURED DOCUMENTS

Public Materials

COMPANY & TECHNOLOGY OVERVIEW

Diabetes Cure Research & Cell-Targeting Technology

Biozipcode™ Company Overview

This overview introduces the research and technology of Biozipcode, Inc.

It covers research into abnormal hematopoietic stem cells and bone marrow-derived cells that treats diabetes as more than a blood glucose disorder, as well as Biozipcode™ cell-targeting technology for recognizing particular cells and tissues.

It also outlines potential applications beyond diabetes, including cancer, diagnostics and biomarkers, DDS, and tissue regeneration.

Contents

Diabetes stem cell research / research toward complete diabetes remission / Biozipcode™ / in vivo biopanning / cell targeting / cancer targeting / R&D pipeline / academic collaboration / intellectual property

5-ALA RESEARCH

About 5-ALA

Clinical Research & Research Potential

This document summarizes published research on 5-ALA (5-aminolevulinic acid) in relation to heme synthesis, mitochondria, energy metabolism, and glucose metabolism.

Biozipcode, Inc. considers 5-ALA a research candidate in diabetes and metabolic disease, not an established treatment for complete diabetes remission.

Please use it as background on existing human research and its relationship to our diabetes research.

RESEARCH EVIDENCE

Explore the Research Evidence

Our research achievements pages provide more detail on the scientific evidence and intellectual property behind our R&D, beyond the PDF materials.

Read them alongside the documents to follow the path from research hypothesis → scientific evidence → intellectual property → current pipeline.

SELECTED PUBLICATIONS

Selected Publications

Explore representative papers underpinning current diabetes stem cell research and Biozipcode™ cell-targeting technology.

They include research on pancreatic islet neogenesis from 2003; CD106-positive short-term hematopoietic stem cells and diabetic neuropathy from 2021; complete remission in mice with STZ-induced diabetes from 2023; and a 2026 human study examining peripheral blood CD34-positive subsets in type 2 diabetes as a candidate cellular biomarker. The page also covers studies of dorsal root ganglia (DRG), spinal cord, microglia, and cancer targeting related to Biozipcode™.

PATENTS & INTELLECTUAL PROPERTY

Patents & Intellectual Property

Explore intellectual property intended to advance research findings in diabetes therapies, abnormal stem cells, diagnostics and detection, and HDAC modulation toward therapeutic and diagnostic technologies.

The public page describes major international application families including PCT/JP2020/039044, PCT/JP2020/039045, PCT/JP2022/008036, and PCT/JP2022/040140, along with an IP strategy for Biozipcode™ combining targeting peptide sequences, uses, payload combinations, DDS, analyses, and know-how.

VIDEOS & PRESENTATIONS

Videos, Lectures & Presentations

Explore videos, conference presentations, lectures, seminars, and media coverage on diabetes stem cells, research toward complete remission, Biozipcode™, and cell targeting.

The collection includes specialist research presentations and accessible introductions to the background of the work.

BIOZIPCODE™ RESEARCH

Explore Biozipcode™ in More Detail

Biozipcode™ is a cell-targeting technology that seeks short peptides recognizing particular cells and tissues for potential diagnostic and therapeutic applications.

It combines phage display, in vivo biopanning, NGS, and bioinformatics to discover candidate sequences recognizing target cells and tissues.

For more technical background, visit our research and technology pages and the research information of Kyoto University’s Department of Biocommunication Development.

What to Build and Who It Will Serve

DEVELOPMENT PIPELINE

Where Is the Research Heading Now?

Academic papers and patents document past research.

Biozipcode, Inc. is also connecting those findings to its current R&D pipeline.

Our principal programs include:

  • investigational diabetes remission therapy
  • diabetes stem cell biomarkers
  • investigational Biozipcode™ diabetes cell-targeted therapy
  • investigational cancer cell-targeted therapy
  • cell-targeted tissue regeneration

Our R&D focuses on these programs.

Each pipeline page distinguishes the scientific evidence available today from the human validation, product development, and nonclinical or clinical work still needed.

FOR PARTNERS

Information for Your Area of Interest

For Pharmaceutical Companies & Research Institutions

An overview of our scientific foundation, research maturity, data still needed, intellectual property, and opportunities for collaborative research and co-development.

For Prospective Research Collaborators

Explore topics for joint validation, including human studies of diabetes stem cells, new Biozipcode™ peptide discovery, biomarkers, DDS, cancer, and regenerative medicine.

For Prospective Licensees

Learn how we approach technology transfer involving diabetes-related intellectual property, Biozipcode™, and biomarkers, supported by scientific data and IP.

For Prospective Co-Development Partners

Explore co-development of specific products and services, including research reagents, analysis services, cell-capture systems, cell-targeted DDS, and regenerative materials.

Contact Us

CONFIDENTIAL MATERIALS

About Confidential Research & Business Materials

Biozipcode, Inc. also holds detailed information needed for collaborative research, technology evaluation, and co-development beyond its public materials.

This may include detailed research data, unpublished results, candidate sequences and technical information, IP strategy, product development plans, Target Product Profiles, and nonclinical, CMC, or clinical development plans.

Because these materials may contain confidential information, we do not make them available for public download.

If you are considering a specific research collaboration, license, or co-development project, we can share materials relevant to the proposed work under an NDA where appropriate.

Explore the research in public materials.
Review the evidence on our detailed pages.
Assess specific technology and development information under an NDA.

We follow this staged approach to sharing information.

For Partners

For Partners

Building on diabetes stem cell research and Biozipcode™ cell-targeting technology, we are advancing new diagnostic and therapeutic technologies for difficult-to-treat diseases.

For Pharmaceutical Companies and Research Institutions

We work with pharmaceutical companies and research institutions to advance research, development, and practical applications based on diabetes stem cell research, Biozipcode™, and related research platforms.

Research Collaboration

We conduct collaborative research with universities, research institutions, medical institutions, and companies in fields including diabetes, cancer, regenerative medicine, biomarkers, and drug delivery systems (DDS).

Technology Licensing

We are exploring technology licensing for research findings involving diabetes treatment and diagnosis, abnormal stem cells, HDAC-related technologies, and Biozipcode™.

Co-development

A cell-targeting platform that identifies short peptide sequences recognizing specific cells and tissues for potential diagnostic and drug delivery applications.

Investment and Strategic Partnerships

We are considering strategic investment and equity partnerships that offer business synergies and support research, development, and practical applications over the medium to long term.

Downloads

Access materials on Biozipcode, Inc., its research and technologies, pipeline, research collaborations, licensing, and related topics.